Predict the pathogenicity and impacted molecular mechanisms of non-frameshifting indel variants

MutPred-Indel is a standalone and web application developed to classify human non-frameshifting indels as pathogenic or benign. In addition, it predicts their impact on over 50 different protein properties and, thus, enables the inference of molecular mechanisms of pathogenicity.

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MutPred-Indel web server

The web server can be used for small-scale data sets (at most 100 variants). The webserver requires a modified FASTA format input, wherein each mutation is represented by wildtype and mutant protein sequences.

Download standalone

The standalone executable can be used for genome-scale data sets. As input, the MutPred-Indel software requires the output file from ANNOVAR's program. To install and run MutPred-Indel, you will need about 16 GB of hard disk space and about 8 GB RAM. Click on the link below to download.

Before downloading: please read the MutPred-Indel license agreement.

For Linux (64-bit)